Myeongdong Rejuran: From Types to Selection Criteria — A Complete Guide
Hello,
This is Dr. Hwang Youjoo,
Medical Director of Lijin Clinic.
Lately, one phrase I hear often in the consultation room is:
“After trying many things,
I keep coming back to Rejuran.”
While a wide range of skin boosters
has emerged over time,
many patients eventually return
to what feels like
the “fundamentals”—Rejuran.
Rather than being a passing trend,
Rejuran has established
a solid level of trust
among both local and international patients.
In recent years,
it has also gained consistent attention overseas,
with frequent mentions
among celebrities and global beauty communities,
further reinforcing its reputation.
Today,
I’d like to walk you through everything
- from its core ingredient
to the differences between each type,
and how to choose the most suitable option for your skin
just as I would explain during a consultation.
“The Key to Skin Regeneration: PN”
1. The Key Ingredient of Rejuran: How PN Works
The most important concept to understand
when discussing Rejuran is PN (Polynucleotide).
PN consists of DNA fragments
derived from salmon,
known for their high biocompatibility,
allowing them to interact safely and effectively with human skin.
As we age,
the skin naturally undergoes several changes:
✔️ Slower cellular turnover
✔️ Reduced collagen production
✔️ Loss of elasticity and changes in skin texture
Rejuran works differently
from treatments that simply “fill” the skin.
Instead,
it delivers PN into the dermis,
helping to create an environment
where the skin can restore itself.
It supports tissue repair
and stimulates fibroblasts,
promoting the production of collagen and elastin.
In other words,
this is not a treatment that temporarily fills the surface,
but one that helps restore the skin’s fundamental health.
Because of this mechanism,
results tend to appear gradually over time,
leading to natural and long-lasting improvements
rather than immediate dramatic changes.
2. Types of Rejuran (Healer / HB / I / S)
Rejuran offers several variations,
each designed for specific concerns and skin conditions.
✔️ Rejuran Healer
The original and most fundamental formulation,
based on pure PN.
It focuses on overall skin regeneration,
improving elasticity and texture,
and enhancing overall skin quality.
✔️ Rejuran HB (Hydro Booster)
A combination of PN, hyaluronic acid, and lidocaine.
It offers added hydration and glow
while reducing discomfort during the procedure.
Especially suitable for those
with dry skin or sensitivity to pain.
✔️ Rejuran I (Eye)
A low-viscosity PN formulation
specifically designed for the delicate eye area.
It helps improve fine lines
and elasticity around the eyes
with minimal burden on thin, sensitive skin.
✔️ Rejuran S (Scar)
A high-viscosity PN formulation
targeted for localized concerns
such as acne scars and enlarged pores.
Ideal for areas that require more intensive,
focused treatment.
3. How to Choose the Right Rejuran for You
This is the most important part.
Even within the Rejuran line,
there is no single “best” option for everyone.
The right choice depends on multiple factors, including:
✔️ Your skin condition
✔️ The area of concern
✔️ Sensitivity to discomfort
✔️ Desired outcome (immediate glow vs. long-term improvement)
For example:
- Overall thinning skin and reduced elasticity → Rejuran Healer
- Dryness, glow, and lower pain tolerance → Rejuran HB
- Fine lines around the eyes → Rejuran I
- Scars or enlarged pores → Rejuran S
Even with the same product,
results can vary significantly
depending on how the treatment is planned and performed.
That’s why it’s essential to carefully assess
Skin thickness and elasticity,
Hydration level,
Depth and extent of concern,
and then design a treatment approach
tailored to each individual.
Ultimately,
Rejuran is not just a procedure
it is a regenerative treatment
that should be customized to your skin.
Through a well-planned approach,
you can expect natural, balanced,
and refined improvements over time.
Thank you.
This has been Dr. Hwang Youjoo from Lijin Clinic.
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