Myeongdong Rejuran | PN vs. PDRN — Understanding Salmon DNA Skin Boosters

Rejuran, Skin Boosters, Salmon DNA Injections, PN & PDRN Explained

— Dr. Youjoo Hwang, Chief Director of Lijin Clinic



Hello,
I’m Dr. Youjoo Hwang, Chief Director of Lijin Clinic.

Recently, many patients visiting our Myeongdong skin clinic for skin booster treatments have been asking questions such as:

“Is Rejuran the same as PDRN?”
“Are salmon DNA injections and Rejuran the same treatment?”
“What is the difference between PN and PDRN?”

Since both PN and PDRN are derived from salmon DNA, they are often grouped together under the term “salmon DNA injections.”
However, their molecular structures and the way they work within the skin are actually quite different.

Today, I’d like to explain the difference between PN and PDRN more clearly, especially for patients considering Rejuran, skin boosters, or regenerative treatments in Myeongdong.

What Is PDRN?

A Regenerative Ingredient Commonly Used in Salmon DNA Injections

PDRN consists of relatively short DNA fragments.

Because of its smaller molecular size, it is absorbed more quickly after injection and is commonly associated with faster regenerative support within the skin.

PDRN is mainly used to support:

  • skin recovery
  • tissue repair
  • inflammation control
  • post-procedure healing

Originally, PDRN was widely used in the medical field for wound healing, burn recovery, scar treatment, and tissue regeneration.

Today, it is also commonly used in various skin booster and salmon DNA injection treatments.

How Is PDRN Used in Skin Booster Treatments?

At many Myeongdong skin clinics, PDRN-based skin boosters are often used to support skin recovery and improve overall skin condition.

For example, PDRN may be used for:

  • post-laser recovery treatments
  • calming sensitized skin
  • hydration-focused skin boosters
  • skin barrier recovery care

Rather than dramatically changing skin structure, PDRN is typically used to support healing and improve skin condition during the recovery process.

What Is PN?

The Core Ingredient in Rejuran

PN has a longer DNA chain structure than PDRN, along with a larger molecular size and higher viscosity.

Because of these characteristics, PN tends to remain in the skin longer after injection, allowing for more sustained regenerative stimulation over time.

PN-based treatments are often associated with:

  • improved skin texture
  • enhanced elasticity
  • better skin density
  • hydration support
  • collagen stimulation

Unlike treatments focused mainly on recovery, PN is commonly used in treatments aimed at improving overall skin quality over time.

Rejuran and PN Skin Boosters

When people think of PN treatments, the most representative procedure is usually Rejuran.

Rejuran is a PN-based skin booster treatment that is widely used for improving:

  • fine lines
  • skin texture
  • elasticity
  • skin density
  • overall skin quality

At our Myeongdong skin clinic, many patients choose Rejuran because they prefer gradual, natural-looking skin improvement rather than dramatic or overly aggressive changes.

Instead of creating immediate volume, Rejuran is often used to support healthier-looking, more resilient skin over time.

PN vs. PDRN — What’s the Difference?

PDRNPN
StructureShort DNA fragmentsLonger DNA chains
Molecular SizeSmallerLarger
Main CharacteristicFaster recovery supportLonger-lasting skin improvement
Main RoleRecovery & inflammation supportElasticity, hydration & skin quality improvement
Common UseSalmon DNA injections, regenerative skin boostersRejuran, PN skin boosters

Choosing the Right Skin Booster in Myeongdong

Ultimately, the most important thing is not simply whether a treatment contains PN or PDRN.

The better question is:

“What does my skin actually need right now?”

Some patients may benefit more from recovery-focused treatments, while others may be looking for long-term skin quality improvement through treatments such as Rejuran and PN skin boosters.

Since every skin condition is different, choosing the right skin booster treatment should always begin with a personalized consultation.

Thank you.

— Dr. Youjoo Hwang
Chief Director of Lijin Clinic








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